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High-Protein Spinach and Artichoke Chicken Casserole

High-Protein Spinach Artichoke Chicken

This hearty casserole combines tender chicken with creamy cheeses, spinach, and artichokes for a protein-packed, comforting dinner that's simple to prepare and full of savory flavor.
Prep Time 15 minutes
Cook Time 35 minutes
Total Time 55 minutes
Course casserole, dinner
Cuisine American
Servings 6 people
Calories 470 kcal

Equipment

  • 1 skillet for cooking chicken and vegetables
  • 1 9x13-inch baking dish for baking casserole
  • 1 mixing bowl

Ingredients
  

  • 1.5 pounds boneless skinless chicken breast diced
  • 2 tablespoons olive oil
  • 3 cloves garlic minced
  • 10 ounces fresh spinach chopped
  • 14 ounces artichoke hearts drained and quartered
  • 8 ounces low-fat cream cheese softened
  • 1 cup plain Greek yogurt
  • 0.5 cup low-fat cottage cheese
  • 1 cup shredded part-skim mozzarella cheese
  • 0.5 cup grated Parmesan cheese
  • 1 teaspoon salt
  • 0.5 teaspoon black pepper

Instructions
 

  • Preheat oven to 375°F and lightly grease a 9x13 inch baking dish.
  • Heat olive oil in a large skillet over medium heat; season diced chicken with salt and pepper and cook until no longer pink, about 5 to 7 minutes.
  • Add minced garlic to the skillet and cook for 1 minute.
  • Stir in chopped spinach and cook until wilted, about 2 minutes.
  • Add drained and quartered artichoke hearts, then remove from heat.
  • In a mixing bowl, combine softened cream cheese, Greek yogurt, and cottage cheese until smooth.
  • Fold the chicken and vegetable mixture into the cheese mixture until evenly coated.
  • Transfer the mixture to the prepared baking dish and spread evenly.
  • Sprinkle shredded mozzarella and grated Parmesan on top.
  • Bake for 20 to 25 minutes until bubbly and cheese is golden.
  • Let casserole rest for 5 minutes before serving.

Notes

  • Substitute kale or Swiss chard for spinach if desired.
  • Use cooked rotisserie chicken to save prep time.
  • Add red pepper flakes for extra spice.
  • Store leftovers in an airtight container; refrigerate up to 4 days.