Combine ingredients for the Creole rub and sauce in separate bowls and set aside.
Season the steak and shrimp with the Creole rub and use the sauce for filling and dipping.
Coat cubed ribeye steak and quartered shrimp with avocado oil and Creole rub, then refrigerate to marinate.
Chop poblano, red bell peppers, yellow bell pepper, and slice onion.
Heat avocado oil on a griddle or skillet over medium heat and cook vegetables with light Creole rub seasoning for 6 to 8 minutes until soft and translucent, then set aside.
Cook marinated steak on the griddle over medium heat for 6 to 8 minutes, turning frequently to brown evenly, then keep warm.
Cook seasoned shrimp on the griddle for 4 to 5 minutes, tossing every minute until pink and opaque, then combine with steak and vegetables.
Mix steak, shrimp, and vegetables together on the griddle for a few minutes to meld flavors.
Toast one side of a 14-inch tortilla on the griddle for 1 minute, then flip, add cheese, filling, drizzle Creole sauce, and fold into a half-moon shape.
Toast the quesadilla 2 minutes on each side until golden brown and cheese is melted.
Slice quesadillas into wedges and serve hot with extra Creole sauce for dipping.