Combine water, beer, Cajun seasoning, 1 tablespoon Old Bay, hot sauce, onion, and lemon in a large stockpot and bring to a boil. Simmer for 15 minutes to build flavor.
Add andouille sausage and baby potatoes to the pot and cook for 15 to 20 minutes until potatoes are tender.
Add snow crab clusters, jumbo shrimp, and corn to the pot, fully submerge, and boil for 5 to 7 minutes until shrimp are opaque and cooked through.
In a small saucepan, simmer butter with garlic, lemon juice, remaining Old Bay, parsley, smoked paprika, and hot sauce for 5 minutes to create garlic butter sauce.
Drain the seafood boil using a spider strainer and spread it on a lined tray.
Pour the garlic butter sauce over the seafood boil and toss thoroughly to coat.
Garnish with fresh lemon wedges and serve immediately on the tray or on individual plates.