Okay, picture this: all the best parts of a cheeseburger had a baby with fluffy buttermilk biscuits, and this glorious casserole is what happened. We’re talking seasoned ground beef, melted cheese, pickles (yes, pickles!), and tender biscuit pieces all baked together into one incredible mess of comfort food perfection. It’s like someone took your favorite burger joint and turned it into a cozy casserole that feeds the whole crew.
This is the kind of dish that makes kids do happy dances and adults seriously consider having thirds. It’s messy, it’s cheesy, it’s absolutely ridiculous, and honestly? That’s exactly why it works. Your kitchen will smell like a backyard BBQ, and everyone will be asking for the recipe before they’ve even finished their first bite.
Why You’ll Love This Recipe
- All the burger vibes, zero flipping required
- Feeds a crowd without breaking a sweat
- Kid-friendly but grown-ups lose their minds over it too
- Perfect for potlucks — you’ll be the hero showing up with this
- Uses simple ingredients you probably already have
- Comfort food overload that hits different on busy weeknights
- Leftovers are legendary (if there are any)
The Good Stuff You’ll Need
For the Burger Base:
- 1 lb ground beef (80/20 blend hits the sweet spot)
- 1 medium onion, diced
- 2 cloves garlic, minced
- 1 tsp Worcestershire sauce
- 1 tsp garlic powder
- 1 tsp onion powder
- Salt and pepper to taste
- 2 tbsp ketchup
- 1 tbsp yellow mustard
For the Biscuit Magic:
- 1 can (16 oz) refrigerated buttermilk biscuits, cut into quarters
- 1/2 cup dill pickle relish (trust the process)
- 2 cups shredded cheddar cheese, divided
- 1 cup shredded mozzarella cheese
For the Sauce Situation:
- 1/2 cup mayonnaise
- 2 tbsp ketchup
- 1 tbsp yellow mustard
- 1 tsp pickle juice (yeah, we’re going there)
- 1/2 tsp garlic powder
For the Finishing Touch:
- Extra shredded cheese (because why not?)
- Chopped fresh chives or green onions
- Sesame seeds (optional but very cute)
Let’s Do This
Step 1: Get Your Oven Ready
Preheat to 375°F and grease a 9×13 baking dish. We’re about to make magic happen.
Step 2: Brown That Beef
In a large skillet over medium-high heat, cook ground beef and diced onion until beef is browned and onion is softened, about 6-8 minutes. Drain any excess fat (but leave a little for flavor).
Add garlic, Worcestershire sauce, garlic powder, onion powder, salt, pepper, ketchup, and mustard. Stir and cook for another 2 minutes until everything smells amazing. Set aside.
Step 3: Make the Magic Sauce
In a small bowl, whisk together mayo, ketchup, mustard, pickle juice, and garlic powder. This is your secret weapon sauce that makes everything taste like the best burger ever.
Step 4: Assembly Time
Cut your biscuits into quarters (yes, they’ll look weird, but trust me). In your greased baking dish, layer half the biscuit pieces.
Spread the cooked beef mixture over the biscuits. Dollop the sauce all over (don’t stress about perfect coverage). Sprinkle the pickle relish and 1 cup of cheddar cheese.
Top with remaining biscuit pieces, then cover with remaining cheddar and all the mozzarella. Go heavy on the cheese — this is not the time for restraint.
Step 5: Bake It Till You Make It
Cover with foil and bake for 25 minutes. Remove foil and bake another 15-20 minutes until biscuits are golden brown and cheese is bubbly and slightly crispy on top.
Let it rest for 5 minutes before serving (I know, the anticipation is killing you).
Step 6: Garnish and Glory
Sprinkle with chives or green onions and sesame seeds if you’re feeling fancy. Serve hot and watch people’s minds get blown.
Serving Suggestions
- Serve with a simple side salad to balance out all that cheesy goodness
- Sweet potato fries on the side? Chef’s kiss
- Ice-cold beer or a vanilla milkshake for the full diner experience
- Corn on the cob makes it feel like a proper summer cookout
Switch It Up
Turkey Time: Use ground turkey instead of beef (add extra seasonings since turkey’s more mild)
Bacon Lover: Add crumbled bacon because everything’s better with bacon
Veggie Boost: Throw in some diced tomatoes or sautéed mushrooms
Spicy Situation: Add diced jalapeños or use pepper jack cheese
Breakfast Vibes: Add scrambled eggs and serve for brunch (you’re welcome)
Slider Style: Use dinner rolls instead of biscuits for mini slider vibes
Make-Ahead Tips
- Brown the beef mixture the night before and store covered in the fridge
- Assemble the whole thing (unbaked) up to 24 hours ahead — just add 10 extra minutes to bake time
- Prep all your toppings and store them separately until ready to use
Questions People Actually Ask
Q: Can I use homemade biscuits? A: Absolutely! Just cut them into chunks and follow the same process. Homemade will taste even better.
Q: What if I don’t like pickles? A: Skip the relish and pickle juice. Add some diced tomatoes instead for that burger vibe.
Q: Can I freeze this? A: Baked leftovers freeze okay for up to 3 months, but the biscuits might get a little soggy. Better to freeze the beef mixture and assemble fresh.
Q: Is there a lighter version? A: Use ground turkey, reduce the cheese by half, and swap Greek yogurt for half the mayo in the sauce. But honestly? Sometimes you just gotta live dangerously.
Q: Help, it’s too salty! A: Pickles and cheese are both salty, so go easy on added salt. Taste your beef mixture before assembling.
Print
Chopped Cheeseburger Biscuit Bake
- Total Time: 1 hour 5 minutes
- Yield: 8–10 servings 1x
Description
Okay, picture this: all the best parts of a cheeseburger had a baby with fluffy buttermilk biscuits, and this glorious casserole is what happened. We’re talking seasoned ground beef, melted cheese, pickles (yes, pickles!), and tender biscuit pieces all baked together into one incredible mess of comfort food perfection. It’s like someone took your favorite burger joint and turned it into a cozy casserole that feeds the whole crew.
This is the kind of dish that makes kids do happy dances and adults seriously consider having thirds. It’s messy, it’s cheesy, it’s absolutely ridiculous, and honestly? That’s exactly why it works. Your kitchen will smell like a backyard BBQ, and everyone will be asking for the recipe before they’ve even finished their first bite.
Ingredients
For the Burger Base:
- 1 lb ground beef (80/20 blend hits the sweet spot)
- 1 medium onion, diced
- 2 cloves garlic, minced
- 1 tsp Worcestershire sauce
- 1 tsp garlic powder
- 1 tsp onion powder
- Salt and pepper to taste
- 2 tbsp ketchup
- 1 tbsp yellow mustard
For the Biscuit Magic:
- 1 can (16 oz) refrigerated buttermilk biscuits, cut into quarters
- 1/2 cup dill pickle relish (trust the process)
- 2 cups shredded cheddar cheese, divided
- 1 cup shredded mozzarella cheese
For the Sauce Situation:
- 1/2 cup mayonnaise
- 2 tbsp ketchup
- 1 tbsp yellow mustard
- 1 tsp pickle juice (yeah, we’re going there)
- 1/2 tsp garlic powder
For the Finishing Touch:
- Extra shredded cheese (because why not?)
- Chopped fresh chives or green onions
- Sesame seeds (optional but very cute)
Instructions
Preheat to 375°F and grease a 9×13 baking dish. We’re about to make magic happen.
In a large skillet over medium-high heat, cook ground beef and diced onion until beef is browned and onion is softened, about 6-8 minutes. Drain any excess fat (but leave a little for flavor).
Add garlic, Worcestershire sauce, garlic powder, onion powder, salt, pepper, ketchup, and mustard. Stir and cook for another 2 minutes until everything smells amazing. Set aside.
In a small bowl, whisk together mayo, ketchup, mustard, pickle juice, and garlic powder. This is your secret weapon sauce that makes everything taste like the best burger ever.
Cut your biscuits into quarters (yes, they’ll look weird, but trust me). In your greased baking dish, layer half the biscuit pieces.
Spread the cooked beef mixture over the biscuits. Dollop the sauce all over (don’t stress about perfect coverage). Sprinkle the pickle relish and 1 cup of cheddar cheese.
Top with remaining biscuit pieces, then cover with remaining cheddar and all the mozzarella. Go heavy on the cheese — this is not the time for restraint.
Cover with foil and bake for 25 minutes. Remove foil and bake another 15-20 minutes until biscuits are golden brown and cheese is bubbly and slightly crispy on top.
Let it rest for 5 minutes before serving (I know, the anticipation is killing you).
Sprinkle with chives or green onions and sesame seeds if you’re feeling fancy. Serve hot and watch people’s minds get blown.
Notes
- Serve with a simple side salad to balance out all that cheesy goodness
- Sweet potato fries on the side? Chef’s kiss
- Ice-cold beer or a vanilla milkshake for the full diner experience
- Corn on the cob makes it feel like a proper summer cookout
- Prep Time: 20 minutes
- Cook Time: 45 minutes
Nutrition
- Calories: ~485 kcal
- Fat: ~28g
- Carbohydrates: ~32g
- Protein: ~22g